Primary tumours modulate innate immune signalling to create pre-metastatic vascular hyperpermeability foci

In mouse models of lung metastasis, before the appearance of significant metastases, localized changes in vascular permeability have been observed, which appear to set the stage for tumour growth. However, it is unclear whether this is also true in human patients. Here, we show that MD-2, a corecept...

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Bibliographic Details
Main Authors: Hiratsuka, Sachie, Ishibashi, Sachie, Tomita, Takeshi, Watanabe, Akira, Akashi-Takamura, Sachiko, Murakami, Masato, Kijima, Hiroshi, Miyake, Kensuke, Aburatani, Hiroyuki, Maru, Yoshiro
Format: Artigo
Language:Inglês
Published: Nature Pub. Group 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674255/
https://ncbi.nlm.nih.gov/pubmed/23673638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2856
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