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Primary tumours modulate innate immune signalling to create pre-metastatic vascular hyperpermeability foci

In mouse models of lung metastasis, before the appearance of significant metastases, localized changes in vascular permeability have been observed, which appear to set the stage for tumour growth. However, it is unclear whether this is also true in human patients. Here, we show that MD-2, a corecept...

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Detalhes bibliográficos
Main Authors: Hiratsuka, Sachie, Ishibashi, Sachie, Tomita, Takeshi, Watanabe, Akira, Akashi-Takamura, Sachiko, Murakami, Masato, Kijima, Hiroshi, Miyake, Kensuke, Aburatani, Hiroyuki, Maru, Yoshiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674255/
https://ncbi.nlm.nih.gov/pubmed/23673638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2856
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