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Effects of isoflurane anesthesia on hyperpolarized (13)C metabolic measurements in rat brain

PURPOSE: Commonly used anesthetic agents such as isoflurane are known to be potent cerebral vasodilators, with reported dose-dependent increase in cerebral blood flow and cerebral blood volume. Despite the widespread use of isoflurane in hyperpolarized (13)C pre-clinical research studies, a quantita...

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Main Authors: Josan, Sonal, Hurd, Ralph, Billingsley, Kelvin, Senadheera, Lasitha, Park, Jae Mo, Yen, Yi-Fen, Pfefferbaum, Adolf, Spielman, Daniel, Mayer, Dirk
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674171/
https://ncbi.nlm.nih.gov/pubmed/23086864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.24532
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