Rap2b, a novel p53 target, regulates p53-mediated pro-survival function

The tumor suppressor p53 is a critical regulator of apoptosis and cell cycle arrest/pro-survival. Upon DNA damage, p53 evokes both cell cycle arrest/pro-survival and apoptosis transcriptional programs. The ultimate cellular outcome depends on the balance of these two programs. However, the p53 downs...

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Bibliographic Details
Main Authors: Zhang, Xinyue, He, Yunlong, Lee, Kyoung-Hwa, Dubois, Wendy, Li, Ziqing, Wu, Xiaolin, Kovalchuk, Alexander, Zhang, Weimin, Huang, Jing
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674092/
https://ncbi.nlm.nih.gov/pubmed/23535297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24364
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