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A RUNX2-Mediated Epigenetic Regulation of the Survival of p53 Defective Cancer Cells
The inactivation of p53 creates a major challenge for inducing apoptosis in cancer cells. An attractive strategy is to identify and subsequently target the survival signals in p53 defective cancer cells. Here we uncover a RUNX2-mediated survival signal in p53 defective cancer cells. The inhibition o...
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| Publicado no: | PLoS Genet |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4771715/ https://ncbi.nlm.nih.gov/pubmed/26925584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005884 |
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