cFOS-SOX9 Axis Reprograms Bone Marrow-Derived Mesenchymal Stem Cells into Chondroblastic Osteosarcoma

Bone marrow-derived mesenchymal stem cells (BMSCs) are proposed as the cells of origin of several subtypes of osteosarcoma (OS). However, signals that direct BMSCs to form different subtypes of OS are unclear. Here we show that the default tumor type from spontaneously transformed p53 knockout (p53_...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: He, Yunlong, Zhu, Wentao, Shin, Min Hwa, Gary, Joy, Liu, Chengyu, Dubois, Wendy, Hoover, Shelley B., Jiang, Shunlin, Marrogi, Eryney, Mock, Beverly, Simpson, R. Mark, Huang, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470112/
https://ncbi.nlm.nih.gov/pubmed/28552607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.04.029
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