The effects of DNA double-strand breaks on mouse oocyte meiotic maturation

Both endogenous and exogenous factors can induce DNA double-strand breaks (DSBs) in oocytes, which is a potential risk for human-assisted reproductive technology as well as animal nuclear transfer. Here we used bleomycin (BLM) and laser micro-beam dissection (LMD) to induce DNA DSBs in germinal vesi...

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Detalhes bibliográficos
Main Authors: Ma, Jun-Yu, Ou Yang, Ying-Chun, Wang, Zhong-Wei, Wang, Zhen-Bo, Jiang, Zong-Zhe, Luo, Shi-Ming, Hou, Yi, Liu, Zhonghua, Schatten, Heide, Sun, Qing-Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674088/
https://ncbi.nlm.nih.gov/pubmed/23518501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24311
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