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DNA replication stress-induced loss of reproductive capacity in S. cerevisiae and its inhibition by caloric restriction

In many organisms, attenuation of growth signaling by caloric restriction or mutational inactivation of growth signaling pathways extends lifespan and protects against cancer and other age-related diseases. The focus of many efforts to understand these effects has been on the induction of oxidative...

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Main Authors: Weinberger, Martin, Sampaio-Marques, Belém, Ludovico, Paula, Burhans, William C.
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674084/
https://ncbi.nlm.nih.gov/pubmed/23518504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24232
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