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Progesterone receptors induce FOXO1-dependent senescence in ovarian cancer cells
Loss of nuclear progesterone receptors (PR) and low circulating progesterone levels are associated with increased ovarian cancer (OC) risk. However, PR are abundantly expressed in a significant percentage of serous and endometrioid ovarian tumors; patients with PR+ tumors typically experience longer...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Landes Bioscience
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3674071/ https://ncbi.nlm.nih.gov/pubmed/23574718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24550 |
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