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Progesterone receptors induce FOXO1-dependent senescence in ovarian cancer cells

Loss of nuclear progesterone receptors (PR) and low circulating progesterone levels are associated with increased ovarian cancer (OC) risk. However, PR are abundantly expressed in a significant percentage of serous and endometrioid ovarian tumors; patients with PR+ tumors typically experience longer...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Diep, Caroline H., Charles, Nathan J., Gilks, C. Blake, Kalloger, Steve E., Argenta, Peter A., Lange, Carol A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Landes Bioscience 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674071/
https://ncbi.nlm.nih.gov/pubmed/23574718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24550
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