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Progesterone receptors induce FOXO1-dependent senescence in ovarian cancer cells
Loss of nuclear progesterone receptors (PR) and low circulating progesterone levels are associated with increased ovarian cancer (OC) risk. However, PR are abundantly expressed in a significant percentage of serous and endometrioid ovarian tumors; patients with PR+ tumors typically experience longer...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Landes Bioscience
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3674071/ https://ncbi.nlm.nih.gov/pubmed/23574718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24550 |
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