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Progesterone receptors induce FOXO1-dependent senescence in ovarian cancer cells
Loss of nuclear progesterone receptors (PR) and low circulating progesterone levels are associated with increased ovarian cancer (OC) risk. However, PR are abundantly expressed in a significant percentage of serous and endometrioid ovarian tumors; patients with PR+ tumors typically experience longer...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Landes Bioscience
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3674071/ https://ncbi.nlm.nih.gov/pubmed/23574718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24550 |
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