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LXCXE-independent chromatin remodeling by Rb/E2f mediates neuronal quiescence

Neuronal survival is dependent upon the retinoblastoma family members, Rb1 (Rb) and Rb2 (p130). Rb is thought to regulate gene repression, in part, through direct recruitment of chromatin modifying enzymes to its conserved LXCXE binding domain. We sought to examine the mechanisms that Rb employs to...

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Autors principals: Andrusiak, Matthew G., Vandenbosch, Renaud, Dick, Fred A., Park, David S., Slack, Ruth S.
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674069/
https://ncbi.nlm.nih.gov/pubmed/23574720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24527
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