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LXCXE-independent chromatin remodeling by Rb/E2f mediates neuronal quiescence
Neuronal survival is dependent upon the retinoblastoma family members, Rb1 (Rb) and Rb2 (p130). Rb is thought to regulate gene repression, in part, through direct recruitment of chromatin modifying enzymes to its conserved LXCXE binding domain. We sought to examine the mechanisms that Rb employs to...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3674069/ https://ncbi.nlm.nih.gov/pubmed/23574720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24527 |
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