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Polo-like kinase 1 inhibitors, mitotic stress and the tumor suppressor p53

Polo-like kinase 1 has been established as one of the most attractive targets for molecular cancer therapy. In fact, multiple small-molecule inhibitors targeting this kinase have been developed and intensively investigated. Recently, it has been reported that the cytotoxicity induced by Plk1 inhibit...

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Detalhes bibliográficos
Main Authors: Sanhaji, Mourad, Louwen, Frank, Zimmer, Brigitte, Kreis, Nina-Naomi, Roth, Susanne, Yuan, Juping
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674062/
https://ncbi.nlm.nih.gov/pubmed/23574746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24573
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