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Loss of p21(Cip1/CDKN1A) renders cancer cells susceptible to Polo-like kinase 1 inhibition
The deregulation of Polo-like kinase 1 is inversely linked to the prognosis of patients with diverse human tumors. Targeting Polo-like kinase 1 has been widely considered as one of the most promising strategies for molecular anticancer therapy. While the preclinical results are encouraging, the clin...
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| Foilsithe in: | Oncotarget |
|---|---|
| Main Authors: | , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Impact Journals LLC
2014
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4466638/ https://ncbi.nlm.nih.gov/pubmed/25483104 |
| Clibeanna: |
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