Granulin Exacerbates Lupus Nephritis via Enhancing Macrophage M2b Polarization

BACKGROUND AND AIMS: Lupus nephritis (LN), with considerable morbidity and mortality, is one of the most severe manifestations of systemic lupus erythematosus (SLE). Yet, the pathogenic mechanisms of LN have not been clearly elucidated, and efficient therapies are still in great need. Granulin (GRN)...

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Detaylı Bibliyografya
Asıl Yazarlar: Chen, Xi, Wen, Zhenke, Xu, Wei, Xiong, Sidong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673914/
https://ncbi.nlm.nih.gov/pubmed/23755248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065542
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