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Granulin Exacerbates Lupus Nephritis via Enhancing Macrophage M2b Polarization

BACKGROUND AND AIMS: Lupus nephritis (LN), with considerable morbidity and mortality, is one of the most severe manifestations of systemic lupus erythematosus (SLE). Yet, the pathogenic mechanisms of LN have not been clearly elucidated, and efficient therapies are still in great need. Granulin (GRN)...

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Autores principales: Chen, Xi, Wen, Zhenke, Xu, Wei, Xiong, Sidong
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673914/
https://ncbi.nlm.nih.gov/pubmed/23755248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065542
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