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Granulin Exacerbates Lupus Nephritis via Enhancing Macrophage M2b Polarization

BACKGROUND AND AIMS: Lupus nephritis (LN), with considerable morbidity and mortality, is one of the most severe manifestations of systemic lupus erythematosus (SLE). Yet, the pathogenic mechanisms of LN have not been clearly elucidated, and efficient therapies are still in great need. Granulin (GRN)...

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Detalhes bibliográficos
Main Authors: Chen, Xi, Wen, Zhenke, Xu, Wei, Xiong, Sidong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673914/
https://ncbi.nlm.nih.gov/pubmed/23755248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065542
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