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Granulin Exacerbates Lupus Nephritis via Enhancing Macrophage M2b Polarization

BACKGROUND AND AIMS: Lupus nephritis (LN), with considerable morbidity and mortality, is one of the most severe manifestations of systemic lupus erythematosus (SLE). Yet, the pathogenic mechanisms of LN have not been clearly elucidated, and efficient therapies are still in great need. Granulin (GRN)...

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Autors principals: Chen, Xi, Wen, Zhenke, Xu, Wei, Xiong, Sidong
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673914/
https://ncbi.nlm.nih.gov/pubmed/23755248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065542
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