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Suppression of Gluconeogenic Gene Expression by LSD1-Mediated Histone Demethylation

Aberrant gluconeogenic gene expression is associated with diabetes, glycogen storage disease, and liver cancer. However, little is known how these genes are regulated at the chromatin level. In this study, we investigated in HepG2 cells whether histone demethylation is a potential mechanism. We foun...

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Hlavní autoři: Pan, Dongning, Mao, Chunxiao, Wang, Yong-Xu
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673910/
https://ncbi.nlm.nih.gov/pubmed/23755305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066294
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