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Suppression of Gluconeogenic Gene Expression by LSD1-Mediated Histone Demethylation

Aberrant gluconeogenic gene expression is associated with diabetes, glycogen storage disease, and liver cancer. However, little is known how these genes are regulated at the chromatin level. In this study, we investigated in HepG2 cells whether histone demethylation is a potential mechanism. We foun...

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Detalles Bibliográficos
Main Authors: Pan, Dongning, Mao, Chunxiao, Wang, Yong-Xu
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673910/
https://ncbi.nlm.nih.gov/pubmed/23755305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066294
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