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Suppression of Gluconeogenic Gene Expression by LSD1-Mediated Histone Demethylation

Aberrant gluconeogenic gene expression is associated with diabetes, glycogen storage disease, and liver cancer. However, little is known how these genes are regulated at the chromatin level. In this study, we investigated in HepG2 cells whether histone demethylation is a potential mechanism. We foun...

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Detalhes bibliográficos
Main Authors: Pan, Dongning, Mao, Chunxiao, Wang, Yong-Xu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673910/
https://ncbi.nlm.nih.gov/pubmed/23755305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066294
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