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Monoubiquitination of EEA1 regulates endosome fusion and trafficking
BACKGROUND: Early endosomal autoantigen 1 (EEA1) is a membrane tethering factor required for the fusion and maturation of early endosomes in endocytosis. How the activity of EEA1 is regulated in cells is unclear. RESULTS: Here we show that endogenous EEA1 is prone to monoubiquitination at multiple s...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3673817/ https://ncbi.nlm.nih.gov/pubmed/23701900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3701-3-24 |
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