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The endosome fusion regulator early-endosomal autoantigen 1 (EEA1) is a dimer.

EEA1, an early-endosomal protein originally identified as an autoantigen, is essential for endocytic membrane fusion. It interacts with early endosomes via binding to the membrane lipid phosphatidylinositol 3-phosphate (PtdIns3P) and the active form of the small GTPase Rab5. Most of the EEA1 sequenc...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Callaghan, J, Simonsen, A, Gaullier, J M, Toh, B H, Stenmark, H
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1999
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220083/
https://ncbi.nlm.nih.gov/pubmed/10024533
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