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Tumor-Induced Myeloid-derived Suppressor Cell Function is Independent of IFNγ and IL-4Rα
Myeloid-derived suppressor cells (MDSC) are present in most cancer patients and experimental animals where they exert a profound immune suppression and are a significant obstacle to immunotherapy. IFNγ and IL-4Rα have been implicated as essential molecules for MDSC development and immunosuppressive...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3673533/ https://ncbi.nlm.nih.gov/pubmed/22673957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201142230 |
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