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Tumor-Induced Myeloid-derived Suppressor Cell Function is Independent of IFNγ and IL-4Rα

Myeloid-derived suppressor cells (MDSC) are present in most cancer patients and experimental animals where they exert a profound immune suppression and are a significant obstacle to immunotherapy. IFNγ and IL-4Rα have been implicated as essential molecules for MDSC development and immunosuppressive...

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Hlavní autoři: Sinha, Pratima, Parker, Katherine H., Horn, Lucas, Ostrand-Rosenberg, Suzanne
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673533/
https://ncbi.nlm.nih.gov/pubmed/22673957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201142230
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