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High-mobility group box protein 1 promotes the survival of myeloid-derived suppressor cells by inducing autophagy

Myeloid-derived suppressor cells are immune-suppressive cells that are elevated in most individuals with cancer, where their accumulation and suppressive activity are driven by inflammation. As myeloid-derived suppressor cells inhibit anti-tumor immunity and promote tumor progression, we are determi...

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Pubblicato in:J Leukoc Biol
Autori principali: Parker, Katherine H., Horn, Lucas A., Ostrand-Rosenberg, Suzanne
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Leukocyte Biology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982609/
https://ncbi.nlm.nih.gov/pubmed/26864266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3HI0715-305R
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