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Abnormal recruitment of extracellular matrix proteins by excess Notch3(ECD): a new pathomechanism in CADASIL

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, or CADASIL, one of the most common inherited small vessel diseases of the brain, is characterized by a progressive loss of vascular smooth muscle cells and extracellular matrix accumulation. The disease is ca...

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Bibliographic Details
Main Authors: Monet-Leprêtre, Marie, Haddad, Iman, Baron-Menguy, Céline, Fouillot-Panchal, Maï, Riani, Meriem, Domenga-Denier, Valérie, Dussaule, Claire, Cognat, Emmanuel, Vinh, Joelle, Joutel, Anne
Format: Artigo
Language:Inglês
Published: Oxford University Press 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673461/
https://ncbi.nlm.nih.gov/pubmed/23649698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awt092
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