Blood brain barrier leakage is not a consistent feature of white matter lesions in CADASIL

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a genetic paradigm of small vessel disease (SVD) caused by NOTCH3 mutations that stereotypically lead to the vascular accumulation of NOTCH3 around smooth muscle cells and pericytes. White matter...

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Dettagli Bibliografici
Pubblicato in:Acta Neuropathol Commun
Autori principali: Rajani, Rikesh M., Ratelade, Julien, Domenga-Denier, Valérie, Hase, Yoshiki, Kalimo, Hannu, Kalaria, Raj N., Joutel, Anne
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6873485/
https://ncbi.nlm.nih.gov/pubmed/31753008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0844-x
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