Deleting exon 55 from the nebulin gene induces severe muscle weakness in a mouse model for nemaline myopathy

Nebulin—a giant sarcomeric protein—plays a pivotal role in skeletal muscle contractility by specifying thin filament length and function. Although mutations in the gene encoding nebulin (NEB) are a frequent cause of nemaline myopathy, the most common non-dystrophic congenital myopathy, the mechanism...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Ottenheijm, Coen A. C., Buck, Danielle, de Winter, Josine M., Ferrara, Claudia, Piroddi, Nicoletta, Tesi, Chiara, Jasper, Jeffrey R., Malik, Fady I., Meng, Hui, Stienen, Ger J. M., Beggs, Alan H., Labeit, Siegfried, Poggesi, Corrado, Lawlor, Michael W., Granzier, Henk
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673460/
https://ncbi.nlm.nih.gov/pubmed/23715096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awt113
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars