Oestrogen increases the activity of oestrogen receptor negative breast cancer stem cells through paracrine EGFR and Notch signalling

INTRODUCTION: Although oestrogen is essential for the development of the normal breast, adult mammary stem cells are known to be oestrogen receptor alpha (ER) negative and rely on paracrine signals in the mammary epithelium for mediation of developmental cues. However, little is known about how syst...

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Main Authors: Harrison, Hannah, Simões, Bruno M, Rogerson, Lynsey, Howell, Sacha J, Landberg, Göran, Clarke, Robert B
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672803/
https://ncbi.nlm.nih.gov/pubmed/23497505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3396
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