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Cell cycle regulators cyclin D1 and CDK4/6 have estrogen receptor-dependent divergent functions in breast cancer migration and stem cell-like activity

Cyclin D1 and its binding partners CDK4/6 are essential regulators of cell cycle progression and are implicated in cancer progression. Our aim was to investigate a potential regulatory role of these proteins in other essential tumor biological characteristics. Using a panel of breast cancer cell lin...

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Detalhes bibliográficos
Main Authors: Lamb, Rebecca, Lehn, Sophie, Rogerson, Lynsey, Clarke, Robert B, Landberg, Göran
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3841318/
https://ncbi.nlm.nih.gov/pubmed/23839043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.25403
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