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Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis
INTRODUCTION: Systemic sclerosis (SSc) is more prevalent in women. Our goal is to determine the effects of 17β-estradiol (E2) on the development of fibrosis and to compare circulating levels of estrogens in SSc patients and healthy controls. METHODS: Using primary human dermal fibroblasts, we evalua...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3672719/ https://ncbi.nlm.nih.gov/pubmed/23305385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4140 |
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