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Closing escape routes: inhibition of IL-8 signaling enhances the anti-tumor efficacy of PI3K inhibitors

The phosphoinositide 3-kinase (PI3K) pathway serves as a relay where signals that emanate from the cell membrane are received and converted into intracellular signals that promote proliferation and survival. Inhibitors of PI3K hold promise for the treatment of breast cancer because activation of thi...

詳細記述

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書誌詳細
主要な著者: Juvekar, Ashish, Wulf, Gerburg M
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672703/
https://ncbi.nlm.nih.gov/pubmed/23566381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3400
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