NAAG Peptidase Inhibitor Improves Motor Function and Reduces Cognitive Dysfunction in a Model of TBI with Secondary Hypoxia

Immediately following traumatic brain injury (TBI) and TBI with hypoxia, there is a rapid and pathophysiological increase in extracellular glutamate, subsequent neuronal damage and ultimately diminished motor and cognitive function. N-acetyl-aspartyl glutamate (NAAG), a prevalent neuropeptide in the...

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Main Authors: Gurkoff, Gene G., Feng, Jun-Feng, Van, Ken C., Izadi, Ali, Ghiasvand, Rahil, Shahlaie, Kiarash, Song, Minsoo, Lowe, David A., Zhou, Jia, Lyeth, Bruce G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672358/
https://ncbi.nlm.nih.gov/pubmed/23562458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2013.03.043
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