NAAG Peptidase Inhibitor Reduces Cellular Damage in a Model of TBI with Secondary Hypoxia

Traumatic brain injury (TBI) leads to a rapid and excessive glutamate elevation in the extracellular milieu, resulting in neuronal degeneration and astrocyte damage. Posttraumatic hypoxia is a clinically relevant secondary insult that increases the magnitude and duration of glutamate release followi...

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Hlavní autoři: Feng, Jun-feng, Gurkoff, Gene G., Van, Ken C., Song, Minsoo, Lowe, David A., Zhou, Jia, Lyeth, Bruce G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424068/
https://ncbi.nlm.nih.gov/pubmed/22750589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2012.06.021
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