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Intracerebroventricular administration of N-acetylaspartylglutamate (NAAG) peptidase inhibitors is analgesic in inflammatory pain

BACKGROUND: The peptide neurotransmitter N-Acetylaspartylglutamate (NAAG) is the third most prevalent transmitter in the mammalian central nervous system. Local, intrathecal and systemic administration of inhibitors of enzymes that inactivate NAAG decrease responses to inflammatory pain in rat model...

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Détails bibliographiques
Auteurs principaux: Yamamoto, Tatsuo, Kozikowski, Alan, Zhou, Jia, Neale, Joseph H
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517065/
https://ncbi.nlm.nih.gov/pubmed/18673570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-4-31
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