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DOWN-REGULATION OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 3 IMPROVES HUMAN ACUTE MYELOID LEUKEMIA-DERIVED DENDRITIC CELL FUNCTION

Signal transducer and activator of transcription (STAT) 3 inhibits dendritic cell (DC) differentiation and is constitutively activated in blasts of approximately half of AML patients. We investigated the correlation between STAT3 activity, DC maturation and the ability to stimulate T-cells in primar...

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Hlavní autoři: Brady, Michael T., Miller, Austin, Sait, Sheila N., Ford, Laurie A., Minderman, Hans, Wang, Eunice S., Lee, Kelvin P., Baumann, Heinz, Wetzler, Meir
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672324/
https://ncbi.nlm.nih.gov/pubmed/23628554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2013.04.002
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