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DOWN-REGULATION OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 3 IMPROVES HUMAN ACUTE MYELOID LEUKEMIA-DERIVED DENDRITIC CELL FUNCTION

Signal transducer and activator of transcription (STAT) 3 inhibits dendritic cell (DC) differentiation and is constitutively activated in blasts of approximately half of AML patients. We investigated the correlation between STAT3 activity, DC maturation and the ability to stimulate T-cells in primar...

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書誌詳細
主要な著者: Brady, Michael T., Miller, Austin, Sait, Sheila N., Ford, Laurie A., Minderman, Hans, Wang, Eunice S., Lee, Kelvin P., Baumann, Heinz, Wetzler, Meir
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672324/
https://ncbi.nlm.nih.gov/pubmed/23628554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2013.04.002
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