DOWN-REGULATION OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 3 IMPROVES HUMAN ACUTE MYELOID LEUKEMIA-DERIVED DENDRITIC CELL FUNCTION

Signal transducer and activator of transcription (STAT) 3 inhibits dendritic cell (DC) differentiation and is constitutively activated in blasts of approximately half of AML patients. We investigated the correlation between STAT3 activity, DC maturation and the ability to stimulate T-cells in primar...

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Detalhes bibliográficos
Main Authors: Brady, Michael T., Miller, Austin, Sait, Sheila N., Ford, Laurie A., Minderman, Hans, Wang, Eunice S., Lee, Kelvin P., Baumann, Heinz, Wetzler, Meir
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672324/
https://ncbi.nlm.nih.gov/pubmed/23628554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2013.04.002
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