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Toxicology and Carcinogenesis Study of Senna in the C3B6.129F1-Trp53(tm1Brd) N12 haploinsufficient mice
Senna is a pod or leaf of Senna alexandrina P. Mill and is used as a stimulant laxative. In the large intestine, bacterial enzymes break sennosides and release rhein-9-anthrone, the active form for the laxative effect. To determine potential toxic effects of senna, a 5-week dose range finding study...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3672319/ https://ncbi.nlm.nih.gov/pubmed/23125117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0192623312464304 |
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