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Acute and subchronic toxicological study of senna in rodents

Senna crude herbal paste, CIRUELAX®, laxative used in America and Spain, was administered by oral gavage to mice and rats once daily in doses from 2 to 10 g/kg for 7 days. LD50 was rated as higher than 10 g/kg. To determine subchronic peroral toxicity (SPT), rats were treated with 1, 2.7 and 6 g/kg...

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Détails bibliographiques
Publié dans:Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas
Auteurs principaux: Juan HANCKE, Dante CÁCERES, Rafael A. BURGOS, Doris HERNÁNDEZ, Armando ROJAS, Miguel A. MORALES
Format: Artigo
Langue:Inglês
Publié: Universidad de Santiago de Chile 2009
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Accès en ligne:https://www.redalyc.org/articulo.oa?id=85611769003
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