Lactobacillus reuteri promotes Helicobacter hepaticus-associated typhlocolitis in gnotobiotic B6.129P2-IL-10(tm1Cgn) (IL-10(−/−)) mice

To model inflammatory bowel disease, we assessed infection with Helicobacter hepaticus 3B1 (ATCC 51449) and a potential probiotic Lactobacillus reuteri (ATCC PTA-6475) in gnotobiotic B6.129P2-IL-10(tm1Cgn) (IL-10(−/−)) mice. No typhlocolitis developed in germ-free controls (n = 21) or in L. reuteri...

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Detalhes bibliográficos
Main Authors: Whary, Mark T, Taylor, Nancy S, Feng, Yan, Ge, Zhongming, Muthupalani, Suresh, Versalovic, James, Fox, James G
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088979/
https://ncbi.nlm.nih.gov/pubmed/21426337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2011.03423.x
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