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MTOR overactivation and interrupted autophagy flux in obese hearts: A dicey assembly?

As a central controller of cell growth, mechanistic target of rapamycin (MTOR) affects an array of biological processes, in particular protein synthesis, autophagy and cardiac homeostasis. Conflicting findings have been seen with regard to the role of MTOR signaling and autophagy in cardiac and adip...

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Autori principali: Zhang, Yingmei, Xu, Xihui, Ren, Jun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672308/
https://ncbi.nlm.nih.gov/pubmed/23529215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.24398
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