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MTOR overactivation and interrupted autophagy flux in obese hearts: A dicey assembly?

As a central controller of cell growth, mechanistic target of rapamycin (MTOR) affects an array of biological processes, in particular protein synthesis, autophagy and cardiac homeostasis. Conflicting findings have been seen with regard to the role of MTOR signaling and autophagy in cardiac and adip...

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Detalhes bibliográficos
Main Authors: Zhang, Yingmei, Xu, Xihui, Ren, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672308/
https://ncbi.nlm.nih.gov/pubmed/23529215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.24398
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