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Repairing DNA damage by XRCC6/KU70 reverses TLR4-deficiency-worsened HCC development via restoring senescence and autophagic flux

Hepatocellular carcinoma (HCC) is among the most lethal and prevalent cancers in the human population. The initiation and progression of HCC is closely associated with chronic liver inflammation. Recent research indicates that nonhomologous end joining (NHEJ), one of the DNA repair mechanisms, autop...

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Autori principali: Wang, Ziyan, Lin, Heng, Hua, Fang, Hu, Zhuo-wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672303/
https://ncbi.nlm.nih.gov/pubmed/23518600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.24229
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