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Glutamate dehydrogenase contributes to leucine sensing in the regulation of autophagy
Amino acids, leucine in particular, are known to inhibit autophagy, at least in part by their ability to stimulate MTOR-mediated signaling. Evidence is presented showing that glutamate dehydrogenase, the central enzyme in amino acid catabolism, contributes to leucine sensing in the regulation of aut...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Landes Bioscience
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3672295/ https://ncbi.nlm.nih.gov/pubmed/23575388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.24083 |
| Oznake: |
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