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Fatty Acids Induce Leukotriene C(4) Synthesis in Macrophages in a Fatty Acid Binding Protein-Dependent Manner

Obesity results in increased macrophage recruitment to adipose tissue that promotes a chronic low-grade inflammatory state linked to increased fatty acid efflux from adipocytes. Activated macrophages produce a variety of pro-inflammatory lipids such as leukotriene C(4) (LTC(4)) and 5-, 12-, and 15-h...

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Bibliographische Detailangaben
Hauptverfasser: Long, Eric K., Hellberg, Kristina, Foncea, Rocio, Hertzel, Ann V., Suttles, Jill, Bernlohr, David A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672270/
https://ncbi.nlm.nih.gov/pubmed/23583845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2013.04.004
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