Identification and Characterization of a Small Molecule Inhibitor of Fatty Acid Binding Proteins

Molecular disruption of the lipid carrier AFABP/aP2 in mice results in improved insulin sensitivity and protection from atherosclerosis. Since small molecule inhibitors may be efficacious in defining the mechanism(s) of AFABP/aP2 action, a chemical library was screened and identified 1 (HTS01037) as...

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Main Authors: Hertzel, Ann V., Hellberg, Kristina, Reynolds, Joseph M., Kruse, Andrew C., Juhlmann, Brittany E., Smith, Anne J., Sanders, Mark A., Ohlendorf, Douglas H., Suttles, Jill, Bernlohr, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755644/
https://ncbi.nlm.nih.gov/pubmed/19754198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm900720m
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