Role of Activated Rac1/Cdc42 in Mediating Endothelial Cell Proliferation and Tumor Angiogenesis in Breast Cancer

Angiogenesis is a well-established target in anti-cancer therapy. Although vascular endothelial growth factor (VEGF)-mediated angiogenesis apparently requires the Rho GTPases Rac1 and Cdc42, the relevant mechanisms are unclear. Here, we determined that activated Rac1/Cdc42 in MCF-7 breast cancer cel...

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Detalhes bibliográficos
Main Authors: Ma, Ji, Xue, Yan, Liu, Wenchao, Yue, Caixia, Bi, Feng, Xu, Junqing, Zhang, Jian, Li, Yan, Zhong, Cuiping, Chen, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672132/
https://ncbi.nlm.nih.gov/pubmed/23750283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0066275
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